Under the background of global warming,The precipitation and temperature had occured significant changes in various regions around the world during the past century。The karst landforms in Guizhou are sensitive to climate change in dry and wet。Studying the century long trend of climate change with representative stations in the area is beneficial to predict future climate and address climate risks。This study is based on the anomalies and relative anomalies of temperature and precipitation in Guiyang over the past century compared to the early climate averages and standard deviations (1921-1950),It has revealed that the dry and wet evolution process of the climate in Guiyang during this period compare to the early climate。The results indicate that the temperature shows a significant warming trend,while the precipitation shows an insignificant decreasing trend in Guiyang during 1921 to2023。The climate has become increasingly warm and dry, with warm and dry climates lasting for 64 and 62 years, including 42 years of warm and dry, 22 years of warm and wet, 19 years of cold and wet, and 20 years of cold and dry. The climate of Guiyang experienced a transition from cold and wet (1921-1936) to warm and wet (1937-1953), with both cold and wet coexisting, with cold and dry predominating (1954-1986) and warm and dry predominating (1987-2011). After 2012, the climate shifted towards warm and humid development。Over the past 103 years, the proportion of years with significant temperature deviations reached one-fifth, with nearly one-third experiencing high temperatures and 11 years experiencing low temperatures. There were also 6 years of abnormal warming and 1 year of abnormal cooling. There was no abnormal year occurred in precipitation,The less of precipitation have 6 years including 1936。and with excessive precipitation has only 1954. The climate in autumn and winter is relatively dry and warm, with autumn being particularly prominent. It has been warm for 74 years and dry for 70 years. Summer is the most stable season for the climate in Guiyang, and the trend of temperature and precipitation changes is not significant. Guiyang have to storage sufficient water in summer to cope with extreme dry and warm weather in autumn and winter in the future。