Taking the meteorological data in China Integrated Meteorological Information Service System (CIMISS) as the data source, an automatic monitoring and alarm system for comprehensive meteorological observation was designed. It could monitor the transmission of observation data in real time and establish the algorithm of observation elements’ threshold to judge whether the meteorological observation data was normal by collecting the historical extreme value, fault and abnormal data observed in regions over the years. Then it pushed the alarm information to the computer terminal and mobile terminal (WeChat) respectively if something wrong was detected, which was convenient for the meteorological staff to check and deal with the fault in time. The system integrated several meteorological monitoring platforms and had good effect on monitoring and warning of meteorological observation data, which greatly improved the efficiency of meteorological station maintenance and the ability of meteorological equipment support. It was of great significance to promote meteorological modernization, intelligence and automation.