The PTB220 and PTB330 air pressure sensors for meteorology are low in efficiency, and there are artificial errors in the verification. A multi-channel air pressure verification system was developed. In the system MOXA-Nport5650-8-DTL serial port server with 8 RS-232/422/485 three-in-one serial ports was adopted to realize synchronous verification and data processing of 8 air pressure sensors, which improves the working efficiency of air pressure verification. Eliminate errors caused by manual checks.