Climate prediction model on glaze disaster over Guizhou in winter was established using the data of daily glaze, the monthly NOAA ERSSTV4 sea surface temperature and NCEP/NCAR reanalysis data during 1961-2015, 500 hPa geopotential height and sea level pressure. Results showed that the glaze disaster was strong/weak when satisfied the condition that the 500hPa geopotential height anomaly field (50°N~70°N, 40°E~80°E) was positive/negative phase and the field (20°N~40°N, 60°E~100°E) was negative/positive phase, while the field (45°N~65°N, 40°E~80°E) of the sea level pressure anomaly was positive/negative phase. In addition, sea surface temperature anomaly in the key area (25°N~35°N, 60°W~40°W) over the North Atlantic Ocean during autumn was negative/positive phase, when the gaze disaster in winter over Guizhou was strong/weak. Additionally, the model in the year with strong glaze disaster was more reliable than that in weak year. The model predicated successfully the intensity of the glaze disaster in winter 2016, which indicated the referential value.